Lumbar Puncture in Emergency Under Nitrous OXide

• Status: Unknown status
• Trial end date: 2020-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Lumbar puncture (LP) is a frequent exam that can cause pain and anxiety. In a scheduled setting, it has been shown that nitrous oxide use during the procedure was able to reduce both pain and anxiety. The goal of this trial is to confirm these results in a more heterogeneous group of patients having a LP, in an emergency setting.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Collaborators: Inserm U1107, NeuroDol; Université Clermont-Auvergne; Université d'Auvergne
• Treatments: Nitrous Oxide

Criteria

Inclusion Criteria:

• Adult patients coming in emergency service who need a lumbar puncture in emergency for a diagnostic purpose

• at least 18

• affiliated to the French state healthcare insurance system

• able to give consent to participation

Exclusion Criteria:

• Previous use of nitrous oxide (medical or recreational)

• Contra-indication to nitrous oxide use

• Face mask phobia

• Stage II obesity (BMI > 35)

• Hemodynamic instability and/or any case when coagulation results cannot be waited

• Cognitive condition defined by a previous Mini Mental State Examination < 24/30

• Confusion or any consciousness disorder that might interfere with judgment or consent

• Patient unable to communicate verbally

• Patient placed under a legal protection measure (tutorship, curatorship or a mandate)

• Any medical condition that might contra-indicate medical research, in physician's opinion