Overview

Lumbar Stenosis Outcomes Research (LUSTOR)

Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
The primary objective of the proposed pilot study is to determine the efficacy of pregabalin in prolonging the time to onset of pain and reducing the severity of pain associated with walking in patients with neurogenic claudication. Neurogenic claudication is defined as movement induced leg pain, numbness, heaviness, or vague discomfort in part or all of one or both legs provoked with walking and standing and relieved by sitting, squatting, or forward flexion posturing. The secondary objective is to examine the functional benefit of pregabalin with respect to improvement in duration and distance of walking.
Phase:
Phase 4
Details
Lead Sponsor:
University of Rochester
Collaborator:
Pfizer
Treatments:
Diphenhydramine
Pregabalin
Promethazine