Lung Cancer Cryo-Activation as a Novel Approach to Augment Immunotherapy Efficacy (CRYOVATE)
Status:
Recruiting
Trial end date:
2023-03-01
Target enrollment:
Participant gender:
Summary
Cryo-activation involves the insertion of a cryoprobe in the tumor bed with subsequent cell
necrosis and tumor antigens release. Such technique has the potential to induce
immune-specific reactions influencing cancer cells outside of the ablated region. The
addition of cryo-activation to immune-checkpoint blockers (ICB) in the advanced NSCLC setting
could represent a synergistic therapeutic avenue in order to potentiate treatment responses