MESNA for Prevention of Acute Deterioration of Renal Function Following Contrast Agent Application

• Status: Completed
• Trial end date: 2004-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine wether Mesna could prevent contrast-induced nephropathy

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Ulm
• Treatments: Mesna

Criteria

Inclusion Criteria:

• stable chronic renal insufficiency

• serum creatinine concentration > 1,5 mg/dl

Exclusion Criteria:

• Dialyzed patients

• patients with acute renal failure

• received iodinated contrast media within 7 days before study entry

• known allery to Mesna, pregnancy, and administration of dopamine, mannitol or N-acetylcysteine