MICARDIS® and Valsartan in Patients With Mild-to-Moderate Hypertension Using Ambulatory Blood Pressure Monitoring
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The primary aim of the trial was to compare the effect of telmisartan and valsartan in
lowering ambulatory diastolic and/or systolic blood pressure in the last six hours of the
dosing interval. Secondary variables included changes from baseline in diastolic and systolic
blood pressures during other times during the 24-hour ABPM profile, changes from baseline in
seated trough diastolic and systolic blood pressures as measured by manual cuff, and
responder rates. Assessment of safety was also considered. Adverse events and use of
concomitant therapies were monitored at each study visit. Blood pressure and heart rate were
collected at each visit. Physical examination, electrocardiograms (ECG) and laboratory tests
were completed during the trial as well.