MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial)

• Status: Unknown status
• Trial end date: 2020-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Acute pulmonary edema (APE) is a common condition in the emergency room, associated with considerable mortality. The use of intravenous morphine in the treatment of APE remains controversial and Benzodiazepines have been suggested as an alternative for morphine to relieving dyspnoea and anxiety in the patients with APE. The MIdazolan versus MOrphine in APE trial (MIMO) is a multicenter, prospective, open-label, randomized study designed to evaluate the efficacy and safety of morphine in patients with APE.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alberto Domínguez Rodríguez; Alberto Dominguez-Rodriguez
• Collaborator: Universidad Europea de Canarias
• Treatments: Midazolam; Morphine

Criteria

Inclusion Criteria:

• Patients with acute pulmonary edema with dyspnoea and anxiety

Exclusion Criteria:

• Patients with known severe liver disease.

• Patients with known severe renal disease.

• Patients with expectation of death from other illness during the course of the trial.