MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005)
Status:
Recruiting
Trial end date:
2022-05-31
Target enrollment:
Participant gender:
Summary
The study will investigate the effects on safety and pharmacokinetics (PK) of MK-1942 and
donepezil when co-administered to participants with Alzheimer's Disease with mild-to-moderate
cognitive impairment stably treated with donepezil. The objectives of this study include
determining if the combination of MK-1942 with donepezil increases the incidence or severity
of adverse events (AEs) previously reported for these agents, or results in unanticipated AEs
in the patient population targeted for MK-1942 treatment. In addition, any changes in the PK
parameters of either MK-1942 or donepezil as a result of co-administration will be assessed.