MOTIV Study- Effect of Antidepressive Treatment by Escitalopram in Patients Undergoing Coronary Artery Bypass Grafting

• Status: Completed
• Trial end date: 2012-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of an antidepressive medication (Escitalopram), started preoperatively and given during 6 months, on 6-month and 1 year post-operative morbidity and mortality after coronary artery bypass grafting

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hopital Jean Minjoz
• Collaborator: H. Lundbeck A/S
• Treatments: Antidepressive Agents; Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Patients undergoing elective coronary artery bypass surgery

• > 30 years old

Exclusion Criteria:

• Contra-indication to antidepressive treatment

• Already treated by antidepressive treatment

• Concomitant cardiac surgery as valve replacement etc.

• Patients having anticoagulation therapy

• Pregnant women

• Hepatic insufficiency