MPA PK Monitoring Strategy With MMF/FK Based Immunosuppression
Status:
Completed
Trial end date:
2006-11-01
Target enrollment:
Participant gender:
Summary
Individuals absorb Cellcept (MMF/Mycophenolate Mofetil) at different rates and it is
difficult to determine an individuals level of Mycophenolate Mofetil (MMF, trade name
Cellcept)from a single measurement. We will enroll 20 subjects. Plasma samples to be
collected pre-MMF dose (trough level) and at 30 and 120 min after the morning dose of
MMF.This will be done weekly for the first month and then monthly for the next 6 mths. We
hope to use a calculation of the subjects total MMF level during the first month to set a
trough target level to use during the next 6 months.