Overview

MRD-guided Treatment in NPM1mut AML Patients

Status:
Recruiting
Trial end date:
2022-08-01
Target enrollment:
Participant gender:
Summary
Evaluation the safety and efficacy of Pembrolizumab (PEM) when administered in combination with standard Azacitidine (AZA) in nucleophosmin (NPM1) mutated AML patients with molecular relapse defined by the presence of measurable residual disease (MRD).
Phase:
Phase 2
Details
Lead Sponsor:
Technische Universität Dresden
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Azacitidine
Pembrolizumab