MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD
Status:
Unknown status
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the efficacy of CD25 monoclonal antibody and
calcineurin inhibitors with or without mesenchymal stem cells (MSCs) in treating patients
with steroid-resistant acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic
stem cell transplantation.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Nanfang Hospital of Southern Medical University
Collaborators:
Academy Military Medical Science, China Guangdong General Hospital Guangdong Provincial People's Hospital Guangzhou First Municipal People’s Hospital Guangzhou First People's Hospital Guangzhou General Hospital of Guangzhou Military Command Huazhong University of Science and Technology Peking University People's Hospital Southern Medical University, China Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Sun Yat-sen University Third Affiliated Hospital, Sun Yat-Sen University