MTD, Safety and Efficacy of NYH817G and NYH100P in Monotherapy and Combination in Patients With Advanced Solid Tumors
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
The objectives of this study are:
Part 1:
- To assess the MTD, safety and efficacy of each NYH817G and NYH100P in monotherapy in
patients with advanced solid tumors who have failed approved standard therapies.
- To assess the PK properties and the preliminary effectiveness of monotherapy of NYH817G
and NYH100P.
Part 2:
- To assess the MTD, RP2D, safety and efficacy of NYH817G and NYH100P in combination
therapy in patients with advanced solid tumors who have failed approved standard
therapies
- To assess the PK properties, the preliminary effectiveness and the changes in metabolism
of combination therapy of NYH817G and NYH100P.