Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease
Status:
Terminated
Trial end date:
2006-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether macrolide therapy is effective in treating
patients hospitalized with asthma exacerbations or chronic obstructive pulmonary disease
(COPD)exacerbations. We hypothesize that compared to placebo, maintenance therapy with
macrolides, when added to usual care, a) improves respiratory symptoms, b) improves quality
of life, c) reduces airway inflammation, d) reduces airflow obstruction, and e) decreases the
rate of re-exacerbations.