Mag Con: Efficacy of Oral Mag. in Acute Concussion in Adolescents

• Status: Recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This randomized trial will compare the clinical efficacy of adding oral magnesium oxide to acetaminophen and ondansetron in the treatment of adolescents presenting within 48 hours of a mild traumatic brain injury using the Post-Concussion Symptom Severity Score Index.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Spectrum Health - Lakeland

Criteria

Inclusion Criteria:

• age 12 to 18 years;

• presenting chief complaint of headache, head injury, or concussion within the first 48 hours of injury;

• GCS > 13 on arrival

Exclusion Criteria:

• age < 12 years or > 18 years;

• inability to provide informed consent;

• vomiting > 2 episodes following injury;

• physical or mental disability hindering adequate response to assessment of symptoms;

• hemodynamic instability/medical condition requiring further acute life-saving medical intervention;

• known brain mass, intracranial hemorrhage, skull fracture;

• known contraindications/allergy to magnesium, ondansetron, or acetaminophen

• pregnant patients