Magnesium Sulfate Dose in Obese Patients.

• Status: Completed
• Trial end date: 2020-11-12
• Target enrollment: 0
• Participant gender: All

Summary

Magnesium sulfate has been applied in various situations due to actual or potential benefits related to neuroprotection, treatment of eclampsia/pre-eclampsia, arterial hypertension, adrenergic reflex under laryngoscopy/intubation and, shivering, nausea and vomiting, among others. In anesthesia it has been useful as an analgesic adjuvant; however, the method to calculate the dose of magnesium sulfate in obese population is unclear. The objective of this project is to compare two methods of dose calculation based either on the real weight or corrected ideal weight.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• Patients aged 18 to 60 year-old

• body mass index > 30 kg/m²

• American Society of Anesthesiologists score < III.

Exclusion Criteria:

• Allergy to any medications of the trial

• refusal to participate or sign the consent form

• any global diagnosed neuromuscular disorder

• cardiac conduction blockade higher than atrioventricular block II

• use of illicit drugs, use of calcium channel blockers

• creatinine > 2 mg/dl.