Magnesium Sulfate For Brain Injury

• Status: Completed
• Trial end date: 2005-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether magnesium sulfate, given within 8 hours of a moderate or severe traumatic brain injury improves survival, decreases the number of people developing seizures, improves the survivors' mental and psychological functioning, including the ability to return to daily life, live independently, and return to work or school.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• Traumatic brain injury with post-resuscitation Glasgow Coma Scale of 3-12 or, if intubated, motor score of 1-5, or who require emergent neurosurgical intervention precluding the accurate assessment of Glasgow Coma Scale.

Exclusion Criteria:

• Injury greater than 8 hours old

• Age under 14 years

• Compromised renal function (creatinine of 2.0 mb/dl or greater)

• Membership in a vulnerable population (e.g. pregnant woman, prisoner, etc.)

• Residence making follow-up unlikely (e.g. lives outside U.S.)

• Refusal to participate