Magnesium Sulfate Versus Placebo for Tocolysis in PPROM

• Status: Terminated
• Trial end date: 2010-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

Study compares the outcomes of women between 26 and 32 wks gestation with rupture of membranes. Women randomized to receive tocolysis with magnesium sulfate x 48 hrs or placebo of saline IV x 48 hrs. Antibiotics and antenatal steroids given to both groups.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Regional Obstetrical Consultants
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• English or Spanish speaking

• preterm premature rupture of membranes

• 26 - 32.6 weeks gestation

• cervical dilation Exclusion Criteria:

• suspected intrauterine or intraamniotic infection

• > 6 hours of tocolysis prior to admission

• positive fetal lung maturity