Magnesium Sulfate in Combination With Dexmedetomidine As Adjuvants to Levobupivacaine

• Status: Enrolling by invitation
• Trial end date: 2021-03-22
• Target enrollment: 0
• Participant gender: Male

Summary

Using the spermatic cord block has been of great advantage, as it has been cost saving, efficient technique whether used inon its own or combination with a sedative or . Furthermore, it provides minimal cardiac risks, early case ambulation, satisfactory postoperative pain control, as well as a reduced hospital stay and cost. one of the major drawbacks of spermatic cord block is being a single injection technique, leading to a short postoperative analgesia duration. So, to overcome this flaw some adjuvants were proven to prolong the analgesia duration as Dexmetedomidine (Dex), and magnesium.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Dexmedetomidine; Magnesium Sulfate

Criteria

Inclusion Criteria:

• Patients aged from 18 to 60 years.

• ASA I-II.

• Undergoing Testicular Sperm Extraction Surgery.

• BMI from 18.5 to 30 kg/m2

Exclusion Criteria:

• Patient refusal

• Contraindications to regional anesthesia (bleeding disorders e.g. INR>1.5, PC<70%, platelet count<100 × 109, use of any anti-coagulants, local infection, etc.).

• Known allergy to local anesthetics.

• ASA III-IV.

• Patients aged less than 18 or more than 60.

• Body mass index >35.

• Patients with difficulty in evaluating their level of pain.