Magnesium Sulfate in Obese Preeclamptics

• Status: Completed
• Trial end date: 2019-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to learn how medications participant will receive in the course of their delivery are metabolized (broken down by the body). The investigators hope to learn more about the way drugs are metabolized by pregnant women, and how those drugs are distributed in the blood and body compartments and cleared in the urine, and how maternal body weight affects the metabolism. With this information the investigators will be able to develop a treatment regimen considering factors in the body that affect magnesium levels so that the investigators can improve treatment of pregnant women. The goal of the study is to understand how different dosing of magnesium sulfate affects blood levels of the magnesium in larger women.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Oregon Health and Science University
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• Pregnant women who are ages 18-45

• 32-42 weeks' pregnant

• Prescribed magnesium sulfate for preeclampsia

• BMI ≥35 kg/m2

Exclusion Criteria:

• Pregnant women < 32 weeks' pregnant

• Women who are on dialysis