Magnesium Sulfate to Prevent Brain Injury in Premature Infants

• Status: Unknown status
• Trial end date: 2003-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Premature infants are at risk for acute brain injuries and long-term developmental problems such as cerebral palsy (CP). Research suggests that high levels of magnesium at and around the time of birth may decrease the risk of brain injuries. This study will evaluate the effects of giving magnesium to premature infants.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria

• Born at 23 to 32 weeks' gestation

• Weighs 500 to 1500 grams (1.1 to 3.3 lbs)

• Requires mechanical ventilation

• Less than 12 hours of age at time of enrollment

Exclusion Criteria

• Multiple congenital anomalies

• Single congenital anomaly of the central nervous system

• Unlikely to be available for duration of the study