Overview

Magnetic Resonance Tumour Regression Grade as Biomarker for Stratified Management of Rectal Cancer Patients

Status:
Recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
This trial evaluates a novel imaging method called magnetic resonance tumour regression grade (mrTRG) to assess how well a tumour has responded to chemoradiotherapy in patients with rectal cancer. The TRIGGER Trial aims to evaluate mrTRG as a tool for stratifying the management of patients according to their response to treatment.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Royal Marsden NHS Foundation Trust
Treatments:
Capecitabine
Fluorouracil
Folic Acid
Leucovorin
Levoleucovorin
Oxaliplatin