Magnetic Sentinel Lymph Node Mapping in Gastric Cancer

• Status: Recruiting
• Trial end date: 2024-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This phase I finds out the possible benefits and/or side effects of using magnetic tracer FerroTrace and the fluorescent dye indocyanine green to identify the lymph nodes that cancer is most likely to have spread to in patients with gastric cancer that are undergoing gastrectomy. Using FerroTrace in combination with the indocyanine green dye may help researchers better detect the disease.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: M.D. Anderson Cancer Center

Criteria

Inclusion Criteria:

• Age 18 or older

• Willing to provide informed consent

• Biopsy proven gastric cancer, undergoing curative-intent gastrectomy

• No distant metastases

• Pathologic diagnosis of gastric adenocarcinoma

• Pre-treatment endoscopic measurement of less than or equal to 4 cm in diameter of the gastric cancer

Exclusion Criteria:

• Contraindications to surgery +/- adjuvant therapy

• Allergy or intolerance to iron oxide compounds

• Allergy or intolerance to iodides

• Iron overload disorder

• Pregnant or lactating women*

• Use of contraception is required for females during the study. Male patients who are sexually active with a female of childbearing potential are allowed for study enrollment and will not require use of contraception