Overview

Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients

Status:
Completed
Trial end date:
2020-05-21
Target enrollment:
0
Participant gender:
All
Summary
This research is intended to begin to explore the impact of inspiratory muscle resistance exercise and/or 1,25(OH)2D3 for improving respiratory muscle strength in cancer patients (subjects).
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Mayo Clinic
Collaborator:
Andersen Foundation
Treatments:
Calcitriol
Dihydroxycholecalciferols
Vitamin D
Criteria
Inclusion Criteria:

- Diagnosis of cancer

- Renal and hepatic function (creatinine normal; bilirubin
- No contraindication to receive either of the planned interventions of inspiratory
resistance training or 1,25(OH)2D3 in the opinion of the healthcare provider

- No difficulties with swallowing oral medications in the opinion of the enrolling
physician

Exclusion Criteria:

- Patient is taking calcium or Vitamin D supplements and is unwilling to stop for 8
weeks

- Severe chronic obstructive pulmonary disease (oxygen dependent or patient self-reports
unable to walk one block without difficulty)

- Calcium or phosphorus level above the institutional upper limit of normal