Maintenance Treatment of Bipolar Depression

• Status: Completed
• Trial end date: 2009-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will compare two different antidepressant treatment regimens to determine which is more effective in reducing symptoms of bipolar depression.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Health Science Center at San Antonio
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Anticonvulsants; Lamotrigine; Valproic Acid

Criteria

Inclusion Criteria:

• Diagnosis of bipolar disorder I or II

• Experiencing symptoms of depression at study entry OR have experienced symptoms of depression within 6 months prior to study entry

• Willing to use acceptable methods of contraception

• Parent or guardian willing to provide informed consent, if applicable

Exclusion Criteria:

• History of liver disease

• History of substance abuse

• Previous treatment with lamotrigine or divalproex

• Lamotrigine or divalproex intolerance