Overview

Management of Preoperative Anaemia in Surgical Oncology

Status:
Recruiting

Trial end date:
2024-08-13

Target enrollment:
0

Participant gender:
All

Summary

Preoperative anemia is detrimental in surgical patients, and its treatment with transfusions can further worsen outcomes, including increased hospital stay and mortality. Transfusions are also highly costly. In 2010, the World Health Organization endorsed the adoption of Patient Blood Management (PBM) programs, i.e., patient-centered multidisciplinary activities, including recognition and treatment of preoperative anemia. While the latter has been proved effective in reducing transfusions in setting like elective orthopedic surgery, widespread adoption is still lacking. Moreover, little is known about surgical oncology, a particular setting posing unique challenging. This change-promoting project attempts to fill this knowledge gap by establishing a multidisciplinary team aimed at optimal management of preoperative anemia in hepatobiliary/pancreas/gastrointestinal/renal surgical oncology. The primary endpoint is the reduction of transfusions, along with safer patient outcomes as compared to the historical series.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Azienda Ospedaliera Universitaria Integrata Verona

Treatments:

Folic Acid
Vitamin B 12

Criteria

Inclusion Criteria:

- Signature of informed consent

- Eligibility to elective surgery for malignant oncological pathology.

- Presence of pre-operative anemia (Hb <12 g/dL females, <13 g/dL males)

- Age >=18 years

Exclusion Criteria:

- Patients with chronic anemia, regularly transfused

- Patients with Hemochromatosis