Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum

• Status: Completed
• Trial end date: 2005-07-01
• Target enrollment: 0
• Participant gender: Male

Summary

This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary.

The purpose of this added procedure (Testicular Aspiration-HOP 3) is to determine the amount of testosterone (male hormone) in the testes of men who are on a male contraceptive regimen.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Washington
• Collaborator: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• Treatments: Acyline; Medroxyprogesterone; Medroxyprogesterone Acetate; Methyltestosterone; Testosterone; Testosterone 17 beta-cypionate; Testosterone enanthate; Testosterone undecanoate

Criteria

Inclusion Criteria:

• Male between 18-55

• In good health

• With normal sperm counts and willing to use an acceptable form of contraception during the study

Exclusion Criteria:

• Male in poor health

• Significant chronic or acute medical illness

• Skin conditions that might interfere with or be exacerbated by testosterone gel

• No history of alcohol, illicit drug or anabolic steroid abuse

• Abnormal reproductive function

• Participation in a long-term male contraceptive study within three months of screening