Mass Vaccine and Drug Administration, Bangladesh

• Status: Not yet recruiting
• Trial end date: 2028-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This is an open i.e. not blinded, cluster-randomised, controlled intervention study. The study will use a factorial design to estimate the protective effectiveness of mass drug administrations, mass vaccinations, combined mass vaccinations and drug administrations versus the current standard of care.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Oxford
• Treatments: Piperaquine

Criteria

Inclusion Criteria:

• Current residence in a study village irrespective of permanence

• Age 6 months and above (no upper age limit)

• Written informed consent provided by participants (or a parent/guardian in case the participant is under 18 years old)

Exclusion Criteria:

• Pregnancy, plan to get pregnant, or breastfeeding.

• Acute illness requiring intervention

• A history of an adverse reaction to study drugs/vaccine and prior receipt of any other malaria vaccine or enrolment in another intervention trial.