Maternal Cardiac Output Response to Rescue Norepinephrine and Phenylephrine Boluses in Patients With Severe Preeclampsia

• Status: Not yet recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to investigate the maternal cardiac output response to rescue norepinephrine and phenylephrine boluses for postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: General Hospital of Ningxia Medical University
• Treatments: Norepinephrine; Oxymetazoline; Phenylephrine; Vasoconstrictor Agents

Criteria

Inclusion Criteria:

• 18-45 years

• Primipara or multipara

• Singleton pregnancy ≥32 weeks

• American Society of Anesthesiologists physical status classification II to III

• Scheduled for cesarean section under spinal anesthesia

Exclusion Criteria:

• Baseline blood pressure ≥180 mmHg

• Body height < 150 cm

• Body weight > 100 kg or body mass index (BMI) ≥ 40 kg/m2

• Eclampsia or chronic hypertension

• Hemoglobin < 7g/dl

• Fetal distress, or known fetal developmental anomaly