Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis

• Status: Completed
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effectiveness of maxillary sinus saline irrigation in conjunction with systemic antibiotic therapy versus systemic antibiotic therapy alone in the management of chronic rhinosinusitis, a prospective randomized controlled trial.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ohad Ronen
• Treatments: Amoxicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Clavulanic Acid; Clavulanic Acids

Criteria

Inclusion Criteria:

• Chronic (over 3 months) maxillary and ethmoidal rhinosinusitis (verified by a CT scan)

• Over 18 years of age

• Signed informed consent

• Not participating in another clinical study

Exclusion criteria:

• A previous sinonasal surgery or craniofacial trauma

• Isolated frontal or sphenoidal sinusitis

• Immunosuppressed (diabetes, cancer, etc.)

• Craniofacial deformity

• Allergic fungal sinusitis

• Nasal polyposis

• Rhinosinusitis of dental origin

• Bleeding tendency (e.g., chronic coumadin treatment)

• Patients participating in other clinical study

• Patients with penicillin allergy

• Patients with Augmentin resistant bacteria in cultures