Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
The overall purpose of this explorative yet quantitative study project is to understand how
blocking IL-6 signaling leads to the expansion of adipose tissue mass in humans in vivo. The
aim is to gain in depth knowledge about how IL-6 receptor blockade affects human lipid,
glucose and protein metabolism, specifically the uptake and storage of substrates from a meal
vs. their utilization, hence the balance determining whether one gains or loses fat mass.