Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing

• Status: Recruiting
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: ou tongwen

Criteria

Inclusion Criteria:

1. Age ≥18

2. Estimated GFR >30 mL/min/1.73m2

3. Subjects who signed informed consent forms

Exclusion Criteria:

1. Allergy to iothalamate, shellfish or iodine

2. Use of metformin or amiodarone

3. Inability to maintain a stable regimen of medications which affect GFR for > one week prior to participation (e.g. non-steroidal anti-inflammatory drugs, angiotensin converting enzyme inhibitors, angiotensin receptor blockers)

4. Use of medications which directly affect elimination of creatinine (e.g. cimetidine and trimethoprim)

5. Acute exacerbation of asthma or chronic obstructive pulmonary disease within 3 months requiring hospitalization or oral steroid therapy

6. Inadequate intravenous access

7. Severe anemia (Hct <21%)

8. Acute kidney injury (rise in creatinine to ≥1.5 times the previous baseline or by ≥ 0.3 mg/dL on most recent labs prior to enrollment)

9. History of contrast-induced nephropathy

10. Hyperthyroidism

11. Pheochromocytoma

12. Sickle cell disease

13. Urinary retention or incontinence

14. Status post organ transplant

15. Pregnancy or active breast feeding

16. Cognitive impairment with inability to give consent

17. Institutionalized status