Overview

Measures to Lower the Stress Response in Pediatric Cardiac Surgery

Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
0
Participant gender:
All
Summary
Cardiac surgery induces a measurable stress response in patients which leads to increased morbidity and mortality post-operatively. Through clinical observation, anesthesiologists have determined that varying the combinations of anesthesia drugs used during surgery and just after reduces the stress response, and by extension, morbidity and mortality. However, only a few studies have explored this phenomenon scientifically.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Nationwide Children's Hospital
Treatments:
Citric Acid
Dexmedetomidine
Fentanyl
Sodium Citrate
Criteria
Inclusion Criteria:

- Childrens with the diagnosis of tetralogy of fallot, ventricular septal defect and
atrioventricular septal defect who are under one year of age.

Exclusion Criteria:

- Patients who are having reoperation.

- Patients with comorbidities, such as heart failure.

- Patients receiving digoxin preoperatively.