Mebeverine For 1st Year Daytime And Nocturnal Incontinence After Orthotopic W-Ileal Neobladders

• Status: Completed
• Trial end date: 2019-05-01
• Target enrollment: 0
• Participant gender: All

Summary

A randomized controlled trial to assess clinically the efficacy of the selective ileum spasmolytic mebeverine on daytime incontinence and nocturnal enuresis of orthotopic w-ileal neobladders and quality of life effect within 1 year post-surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Alverine; Mebeverine

Criteria

Inclusion Criteria:

1. Men 18 years or older

2. ONB within 1 year post-surgery.

Exclusion Criteria:

1. Upper urinary tract deterioration

2. Uncontrolled diabetes mellitus

3. Evident local or pelvic recurrence

4. Adjuvant chemotherapy

5. Chronic retention

6. Pouch stones

7. Urethral stricture or urethro-ileal maldirection

8. Sensitivity to Mebeverine

9. Untreated chronic constipation

10. Active symptomatic urinary infection