Mechanisms of CBD for Chronic Pain

• Status: Recruiting
• Trial end date: 2022-02-28
• Target enrollment: 0
• Participant gender: All

Summary

This is a study designed to examine the neurochemical mechanisms associated with Cannabidiol (CBD) versus placebo for chronic non-cancer pain.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Utah
• Treatments: Cannabidiol; Epidiolex

Criteria

Inclusion Criteria:

• Age between 18-50 yrs.

• Chronic musculoskeletal and joint pain for at least 3 months or longer.

• Participants must live within a 60 mile radius of Salt Lake City, Utah to be eligible.

Exclusion Criteria:

• Current or past neurological illness.

• Substance abuse or dependence within the prior 90 days.

• Contraindication to brain MRI.

• Type I and type II diabetes.

• Unstable medical conditions.

• Consumption of more than 2 drinks of alcohol per night.

• Current pregnancy or planning to become pregnant or breastfeeding.

• History of seizures or head trauma at PI discretion.

• Active or history of major mental illness

• Use of opioid medications in the past 30 days.

• LFT results 3 times greater than the upper limit of normal at the screening.

• Participants may be excluded if the PI feels they do not meet safety criteria.