Median Effective Dose of Dexmedetomidine in Elective Upper Limb Lidocaine Intravenous Regional Anesthesia

• Status: Completed
• Trial end date: 2020-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Auxiliary drugs augment the effect of local anesthetic in intravenous regional anesthesia (IVRA). The purpose of our study was to estimate the median effective dose (ED50) of Dexmedetomidine in elective upper limb Lidocaine 0.5% IVRA.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: South Valley University
• Collaborator: Tanta University
• Treatments: Anesthetics; Dexmedetomidine; Lidocaine

Criteria

Inclusion Criteria:

• Aged between 18 and 60 years

• American Society of Anesthesiologists physical status I or II

• Undergoing minor upper limb orthopedic surgical procedures in the hand, wrist and forearms including: metacarpal fracture, tendon injury, and carpal tunnel release.

Exclusion Criteria:

• Allergy to test drugs.

• vascular disease.

• contraindication to tourniquet applications.

• difficulty to manipulate the surgical limb.

• surgery expected to last more than an hour.

• patient refusal