This is the first randomized parallel group clinical trial looking at oral prednisolone
induced medical nasal polypectomy followed by maintenance on topical steroid therapy in
patients with nasal polyposis. This study also looks at the effect of aspirin sensitivity and
the factors linking nasal polyps with asthma. We have also taken baseline measurements of a
variety of blood, surface and biopsy markers to assess for potential to predict steroid
response. Finally, the still unchartered link between nasal polyps and asthma will be
explored by measuring Staphylococcal superantigens in serum before and after treatment.
Phase:
Phase 4
Details
Lead Sponsor:
University of Dundee
Collaborators:
Chief Scientist Office of the Scottish Government NHS Tayside