Medical Thoracoscopy for Undiagnosed Transudative and Exudative Pleural Effusions
Status:
Not yet recruiting
Trial end date:
2023-09-30
Target enrollment:
Participant gender:
Summary
Indonesia is one of country that contributes the most cases of tuberculosis worldwide.
Tuberculosis is the most commonly etiology of exudative pleural effusion. There have been
many studies about undiagnosed exudative pleural effusions, but there are not many studies
about the use of medical thoracoscopy for diagnosing transudative and exudative pleural
effusion, especially on biomarkers of C-Reactive Protein (CRP), D-dimer, Adenosine Deaminase
(ADA), Antinuclear Antibody (ANA), C3 C4 complements, Cancer Antigen 125 (CA-125), Xpert
Mycobacterium Tuberculosis (Xpert MTB), Lupus Erythematosus cell (LE cell), cytology
(effusion and smear) and histopathology. Information gained from those biomarkers via
thoracocentesis and medical thoracoscopy, etiology of exudative and transudative pleural
effusion can be detected earlier and clearly, especially etiology of infection, autoimmune,
and malignancy that further can be used to reduce patients' hospitalization period,
mortality, and to develop the new therapeutic agents.
Phase:
N/A
Details
Lead Sponsor:
Indonesia University
Collaborator:
Singapore General Hospital
Treatments:
Complement C4 Complement System Proteins Fentanyl Lidocaine Midazolam