Medium vs Low Oxygen Threshold for the Surfactant Administration
Status:
Not yet recruiting
Trial end date:
2025-04-30
Target enrollment:
Participant gender:
Summary
The aim of this study will be to assess the better fraction inspired oxygen (FiO2) threshold
for the surfactant treatment in preterm infants with respiratory distress syndrome (RDS)
randomized to receive exogenous surfactant at 25% or 35% of FiO2 threshold. The pulmonary
gas-exchanges will be evaluated by oxygen saturation (SpO2) to FiO2 ratio (SFR) and will be
used to define the better FiO2 threshold for the surfactant treatment.