Melatonin Treatment After Laparoscopic Cholecystectomy

• Status: Completed
• Trial end date: 2006-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Circadian disturbances occur after surgery. A double blinded, placebo controlled randomized clinical trial was made to investigate effects of melatonin on postoperative fatigue, sleep disturbances and general wellbeing.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Gentofte, Copenhagen
• Treatments: Melatonin

Criteria

Inclusion Criteria:

• Operation for gall bladder disease

• Age over 18 years

Exclusion Criteria:

• Known preoperative sleep disturbance

• Anticoagulant therapy

• Psychiatric disease

• Lack of written informed consent

• Treatment with hypnotics within one week prior to surgery