Melatonin Use After Primary Total Joint Arthroplasty

• Status: Not yet recruiting
• Trial end date: 2022-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of melatonin supplementation on patient sleep quality, length of stay, and opioid consumption following primary, unilateral, elective total hip or knee arthroplasty.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: NYU Langone Health
• Treatments: Melatonin

Criteria

Inclusion Criteria:

• Patient are current candidates for elective primary total hip and total knee arthroplasty.

• Patients ≥18 years of age but ≤ 95

• Patients have been medically cleared and scheduled for surgery

Exclusion Criteria:

• Non-elective conversion arthroplasty

• Bilateral total joint arthroplasty

• Contraindications to use of melatonin (diabetes, calcium channel blocker use, depression)

• Conditions and medications likely to confound results due to impact on subjective and/or objective sleep quality (insomnia, drug/alcohol abuse, and use of benzodiazepines, and prescription sleep aids)

• Conditions likely to impair capacity to adhere to protocol (mental impairment, psychiatric disorders other than anxiety/depression)