Melatonin for Post Operative Delirium Prevention in Elderly Patients

• Status: Recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study will evaluate the role of melatonin prophylaxis in delirium prevention in elderly patients undergoing colorectal procedures.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University
• Treatments: Melatonin

Criteria

Inclusion Criteria:

• American Society of Anaesthesiologists (ASA) I to III physical status

• Elective colorectal procedures

Exclusion Criteria:

• Allergy to the research drugs,

• Patients who have vision or hearing impairment

• History of cerebral disorders

• Uncorrected acid-base, fluid, and electrolyte abnormalities

• History of central nervous system function affecting drugs.

• Chronic sedative-hypnotic administration at least one month prior to surgery

• Alcohol abuse

• Patients with recorded preoperative nursing delirium screening score ≥ 2.