Melatonin in Smoke-induced Vascular Injury

• Status: Completed
• Trial end date: 2015-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The main purpose of this study was to evaluate the effects of melatonin in the regulation of the vascular injury in smokers through population-based, randomized, double-blind, placebo-controlled trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Peking Union Medical College Hospital
• Treatments: Melatonin

Criteria

Inclusion Criteria:

• Healthy smokers：must above 10 cigarettes per day, at least 1 year

• Healthy non-smokers

Exclusion Criteria:

• Cardiovascular disease

• Systolic blood pressure above 140 mm Hg

• Diastolic blood pressure above 90 mmHg

• Psychiatric disorders

• Cancer

• Pregnant

• Lactating

• Taking antipsychotic drugs orally during the 2 weeks of the trial