Overview Melphalan in Patients With Neoplastic Meningitis Status: Completed Trial end date: 2001-05-01 Target enrollment: Participant gender: Summary RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of melphalan in patients with persistent or recurrent neoplastic meningitis. Phase: Phase 1 Details Lead Sponsor: Duke UniversityTreatments: Melphalan