Overview

Memantine Versus Placebo in Parkinson's Disease Dementia or Dementia With Lewy Bodies

Status:
Completed

Trial end date:
2009-01-01

Target enrollment:
0

Participant gender:
All

Summary

The purpose of this exploratory study is to determine whether memantine can provide benefits on clinical symptoms in patients with Parkinson's Disease Dementia or Dementia with Lewy Bodies.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

H. Lundbeck A/S

Treatments:

Memantine

Criteria

Inclusion Criteria:

- The study population will consist of male or female outpatients at least 50 years of
age with mild to moderate disease severity (MMSE 12 to 24 inclusive) according to
UKPDS and DSM IV TR criteria (for PDD patients) and the third report of the DLB
consortium (for DLB patients) and who have a knowledgeable and reliable caregiver to
accompany the patient to all clinic visits during the course of the study.

Exclusion Criteria:

- Evidence of clinically significant active disease, evidence of other neurological
disorders, and current treatment with AChEIs.