Memantine and Cognitive Dysfunction in Bipolar Disorder
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see whether memantine improves memory function in
participants with bipolar disorder who have minimal symptoms. Secondary analyses will test
the role of memantine in improving residual mood symptoms (depression and mania) in
participants with bipolar disorder.
We hypothesize that in participants with bipolar disorder who have minimal symptoms memantine
will be effective in improving cognitive functions, as measured by the difference in
neuropsychological test scores at the beginning and at the end of the trial.
Phase:
Phase 4
Details
Lead Sponsor:
Cedars-Sinai Medical Center Massachusetts General Hospital
Collaborators:
Forest Laboratories Massachusetts General Hospital Northwestern University