Meperidine Versus Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae

• Status: Unknown status
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: Male

Summary

Comparison Between Meperidine and Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Drotaverin; Meperidine; Papaverine

Criteria

Inclusion Criteria: ● primigravida.

• Singleton pregnancy.

• Term gestation i.e, 38-41 weeks.

• Sure, reliable dates documented by ultrasound in the 1st half of pregnancy.

• Vertex presentation with occipito anterior position.

• Efficient uterine contractions at a rate of at least 3 to 4 contractions every 10 minutes, each contraction lasting for at least 40 seconds.

Exclusion Criteria: ● Abnormal presentation or occipito posterior position.

• Multiple pregnancies.

• Cephalo-pelvic disproportion.

• Cervical surgery in the past or history of cervical injury.

• Patients on antihypertensive therapy.

• Known hypersensitivity to drotaverine or meperidine.

• If any other spasmolytic agent had been used within 48 hours.