Metabolic Capacity of Israeli Populations

• Status: Unknown status
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The ability to metabolize drugs varies greatly among individuals. Major fraction of this variability lies in genetic polymorphisms of genes encoding for enzymes responsible for both phase I and phase II reactions.

The purpose of this study ws to evaluate the phenotypic activity and the frequency of genetic polymorphisms in different phase II and phase I enzymes among various populations residing in Israel.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hadassah Medical Organization
• Treatments: Caffeine; Dapsone; Debrisoquin; Mephenytoin

Criteria

Inclusion Criteria:

• Age range 20-50

• Absence of significant disease state

Exclusion Criteria:

• The presence of significant disease states

• The regular use of drugs (including birth control pills)