Metabolic Impact Assessment of Tenofovir Disoproxil Fumarate on Non-HIV-1 Infected Healthy Adult Male Volunteers
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
Metabolic changes commonly occur in HIV therapy. The purpose of this study is to assess the
impact on insulin sensitivity from the administration of tenofovir disoproxil fumarate 300 mg
compared with placebo in non-HIV-1 infected healthy adult males. Additionally, endothelial
function, adipocytokines and lipids will be monitored.