Conventional measures used for the treatment of chronic heart failure act predominantly by
reducing the work performed by the heart. In a recent study, the investigators showed that
one drug (perhexiline) substantially improved symptoms and cardiac function in heart failure.
The investigators wish to confirm these findings and test whether or not this drug acts by
altering the heart's energy source thus augmenting the energetic status and work efficiency
of the heart.
Phase:
Phase 2
Details
Lead Sponsor:
University Hospital Birmingham NHS Foundation Trust