Metabolism of 0.35mg Norethindrone vs 5mg Norethindrone Acetate
Status:
Not yet recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
0.35mg norethindrone, also known as progesterone only pills, are routinely prescribed as
immediate postpartum oral contraception. Norethindrone acetate is prescribed for gynecologic
indications, but has never been studied as an efficacious form of contraception. This is a
pilot crossover study examining the pharmacokinetics of norethindrone, the metabolically
active component of both drugs, in participants taking 5mg norethindrone and 0.35mg
norethindrone acetate.